中年および高齢の慢性腎臓病患者の口腔の弱さの流行と影響因子:横断的な研究
Yuelin Wang1, Zengli Chen2, Qing Tang3
1College of Nursing, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Frontiers in medicine
|September 2, 2025
まとめ
慢性腎臓病 (CKD) の患者では,口腔の脆弱性が一般的であり,60%以上に影響します. 婚姻状況や口の乾燥などの要因は リスクを増大させ,CKDのケアにおいて 標的を絞った口腔衛生介入の必要性を強調しています
科学分野:
- ゲロントロジー
- 腎臓科
- 口腔 衛生
背景:
- 慢性腎臓病 (CKD) の治療において,口腔の健康状態の低下と全身の弱さのマーカーである口腔の弱さは十分に研究されていない.
- 慢性腎臓病の患者は,慢性腎臓病のない人と比較して,口腔の健康状態が悪くなります.
研究 の 目的:
- 中年および高齢のCKD患者における口腔の弱さの有病率を決定する.
- この患者集団における口腔の弱さに関連する要因を特定する.
主な方法:
- 307人のCKD患者の横断的な研究が行われました.
- 口腔の脆弱性は,口腔の脆弱性指数-8 (OFI-8) を用いて評価された.
- 栄養状態,疲労,不安,およびうつに関するデータは,それぞれMNA- SF,RPFS,およびHADSを使用して収集されました. ロジスティック・リグレーションで関連した要因が特定された.
主要な成果:
- 慢性腎臓病患者の口腔の弱さの罹患率は61. 9% (190/ 307) であった.
- 口の弱さの重要な危険因子には,婚姻状況,教育レベル,自己ケア能力,義歯の使用,口の乾燥,および疲労 (RPFS-CVスコア) が含まれていた.
結論:
- 慢性腎臓病の患者では口腔の脆弱性が高い.
- 医療従事者は,高リスクグループに焦点を当てて,慢性腎臓病における口腔の弱さの予防と管理のためのカスタマイズされた戦略を実施すべきである.
関連する概念動画
Chronic Kidney Disease II: Clinical Manifestations
85
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
85
Chronic Kidney Disease I: Introduction
65
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
65
Chronic Kidney Disease III: Interprofessional Care
77
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
77
Factors Affecting Renal Clearance: Renal Impairment
154
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
154
Bone Disorders
3.9K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.9K
Chronic Kidney Disease IV: Nursing Management
54
Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
54


