ワクチン接種ではなくSARS-CoV-2感染がCOVID-19と心筋梗塞の死亡率との真の関連である:エクアドル全国の研究
Esteban Ortiz-Prado1, Vladimir Ullauri Solorzano2, Diana Moreira-Vera2
1One Health Research Group, Faculty of Health Science, Universidad de Las Americas, Quito, Ecuador.
International journal of cardiology. Cardiovascular risk and prevention
|September 2, 2025
まとめ
エクアドルでは,ワクチン接種ではなくCOVID-19感染が心臓発作 (MI) による死亡率の増加と関連しています. COVID-19ワクチンは,誤った情報に対抗し,予防接種の取り組みを支援し,保護効果を示しました.
科学分野:
- 心血管疾患の疫学
- 感染症の疫学
- 公衆衛生研究
背景:
- COVID-19ワクチンと心筋梗塞 (MI) を関連付ける誤った情報は,特にエクアドルのような高死亡率地域では,ワクチン接種の躊躇性を高めています.
- この研究は,エクアドルにおけるCOVID-19感染,ワクチン接種,心筋梗塞の死亡率の関係を調べることで,懸念を解決しています.
研究 の 目的:
- エクアドルにおけるCOVID-19ワクチン接種または感染と心筋梗塞による死亡率の増加との関連を調べる.
- ワクチンに関する誤った情報に対抗するため,証拠に基づいた情報を提供すること.
主な方法:
- 記述的,観察的,生態学的タイムシリーズの研究では,710日間の国家健康登録データ (2021年1月〜2022年12月) を分析した.
- MI死亡,COVID-19死亡,COVID-19ワクチン接種の毎日のカウントが収集されました.
- タイムシリーズ回帰モデルは,性別に分類されたMI死亡率とCOVID-19死亡率/ワクチン接種率の関連性を評価した.
主要な成果:
- 合計26,637人のMI死亡と24,066人のCOVID-19死亡が記録されました.
- 毎日発生するCOVID-19による死亡率は著しく増加した (β=0.08667,p<0.0001),女性の死亡率はより高かった.
- COVID-19のワクチン接種率は,小規模だが,ミーム性脳卒中の死亡率に対する有意な保護効果を示した (β=-1.188e-5,p=0.0218).
結論:
- エクアドルでは,ワクチン接種ではなくCOVID-19感染が,心臓発作による死亡率の増加と強く関連しています.
- 予防接種は保護効果を示し,心血管の安全性と公衆衛生の重要性を強調した.
- ワクチンをMIと結びつける誤った情報を否定し,高リスク環境での予防接種キャンペーンを支援しています.
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