関連する実験動画

Updated: Sep 9, 2025

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model
08:15

Network Pharmacology and Validation of the Antidepressant Mechanisms of Qiangzhifang in a Chronic Restraint Stress-induced Depression Rat Model

Published on: June 6, 2025

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鬱病に対するエスケタミンの影響:BDNF/TrkB/PI3K/AKT経路の活性化による酸化ストレスとニューロンアポトーシスの標的化

Yueyi Zhang1, Qianqian Cai2, Lingshan Wang3

  • 1Tianjin Medical College Pharmacy and Biotechnology Department, Tianjin, People's Republic of China.

Neuropsychiatric disease and treatment
|September 2, 2025
PubMed
まとめ

エスケタミンの治療は,脳由来神経栄養因子 (BDNF) /TrkB/PI3K/AKT経路を活性化することによって,うつ病を効果的に軽減します. このメカニズムは神経損傷と 酸化ストレスを軽減し 治療に抵抗するうつ病の 治療に抵抗するうつ病の 治療に抵抗するうつ病の 治療に抵抗するうつ病の

キーワード:
BDNF/TrkB/PI3K/AKTについてCUMSラットうつ病エスケタミン酸化ストレス

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