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Updated: Sep 9, 2025

Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding
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ガルブリミマアルカロイドの双方向的修正は,選択的なオピオイドリガンドを識別する

Florian Martin Zielke1, Stone Woo1,2, Samuel Kasmali1,2

  • 1Department of Chemistry, Scripps Research, La Jolla, California 92037, United States.

ACS central science
|September 2, 2025
PubMed
まとめ

研究者は新しいオピオイド抗体であるGB18を選択的なカッパ・オピオイド受容体 (KOR) アゴニストに最適化しました. これらの化合物は,副作用のプロファイルが改善された新しい痛み治療薬の開発に希望を示しています.

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