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Updated: Sep 9, 2025

Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity
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Interrogating Individual Autoreactive Germinal Centers by Photoactivation in a Mixed Chimeric Model of Autoimmunity

Published on: April 11, 2019

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防御性耐性は,浸透した病原性B細胞の再プログラムと機能障害を誘導し,耐性の維持を保証する

Koki Hayashi1,2,3, Takahiro Yokose1,2,3, Jenna Lancey1,2,3

  • 1Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital and Harvard Medical School; Boston, MA, USA.

Research square
|September 2, 2025
PubMed
まとめ

調節性B細胞 (Bregs) は移植耐性を引き起こさない. 代わりに,B細胞のFcγRIIBとSiglec-Gは移植受容と腫瘍免疫回避の鍵となる.

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In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients

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