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Updated: Sep 9, 2025

Generation of Prostate Cancer Cell Models of Resistance to the Anti-mitotic Agent Docetaxel
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Generation of Prostate Cancer Cell Models of Resistance to the Anti-mitotic Agent Docetaxel

Published on: September 8, 2017

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EZH2-TTP-mTORC1軸は,致死性前立腺がんにおけるフェノタイプの可塑性および治療的脆弱性を駆動する

Leigh Ellis, Beatriz German, Katherine Morel

    Research square
    |September 2, 2025
    PubMed
    まとめ

    前立腺がんのフェノタイプ性可塑性 (PCa) は抵抗を誘発する. この致命的なPCaサブタイプに対して,ゲーストホモログ2 (EZH2) とPI3K/mTORC1の標的化強化剤は有望である.

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