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Updated: Sep 9, 2025

Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia
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Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia

Published on: December 22, 2023

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ダントロレンによるライアノジン受容体の阻害は,構造性心疾患の患者における心室短拍の誘発を防ぐ - ランダム化比較試験

Majd A El-Harasis, Zachary T Yoneda, Bibin Varghese

    medRxiv : the preprint server for health sciences
    |September 2, 2025
    PubMed
    まとめ

    構造的な心臓病の患者では,ダントロレンは心室性短拍 (VT) の誘導性を有意に低下させた. この研究は,良質な安全性プロファイルを持つ不律症の予防のためのライオノジン受容体-2 (RyR2) の標的化を支持する.

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