関連する実験動画

Updated: Sep 9, 2025

Isolation of Pulmonary Artery Smooth Muscle Cells from Neonatal Mice
08:02

Isolation of Pulmonary Artery Smooth Muscle Cells from Neonatal Mice

Published on: October 19, 2013

18.5K

ヘリオックス・プリコンディショニングは,新生児の急性呼吸障害症候群に酸化ストレスとアポトーシスを阻害することによって,肺の保護効果を発揮する

Juan Ma1,2, Leilei Shen3, Yuan Shi1

  • 1Department of Neonatology Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatric Metabolism and Inflammatory Diseases, Chongqing, China.

Frontiers in pharmacology
|September 2, 2025
PubMed
まとめ

ヘリオックス・プリコンディショニング (HePC) は,新生児の急性呼吸障害症候群 (ARDS) に対して,酸化ストレスとアポトーシスを減少させることで保護します. これは,CaMKII発現を抑制し,CaMKII/ RyR2経路を調節することによって達成されます.

キーワード:
カMK-IIアンチアポトーシス抗酸化ストレスヘリオックスプリコンディショニング新生児急性呼吸器障害症候群

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