関連する実験動画

Updated: Sep 9, 2025

Using the E1A Minigene Tool to Study mRNA Splicing Changes
10:25

Using the E1A Minigene Tool to Study mRNA Splicing Changes

Published on: April 22, 2021

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スプライシングと3'処理の競争がヒトのトランスクリプトームを形作る

Lindsey V Soles, Shuangyu Li, Liang Liu

    bioRxiv : the preprint server for biology
    |September 2, 2025
    PubMed
    まとめ

    mRNA前スプライシングを妨害すると,何千もの内部ポリアデニレーション部位が活性化し,早めに転写が終了します. 逆に,3'処理を抑制すると,スプライシングが全般的に強化され,トランスクリプトームを形作る競争的な相互作用が明らかになる.

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