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Updated: Sep 9, 2025

Method for Efficient Refolding and Purification of Chemoreceptor Ligand Binding Domain
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FBXO22のためのリクルートメントリガンドとしてのデグラダーと2-ピリジンカルボキシアルデヒド (2-PCA) の開発

Tian Qiu, Zhe Zhuang, Woong Sub Byun

    bioRxiv : the preprint server for biology
    |September 2, 2025
    PubMed
    まとめ

    研究者らは,標的型タンパク質分解 (TPD) のための新しい化学探査機を開発した. これらの探査機はFBXO22を 選択的に分解したり TPDに利用したりして 癌の研究や治療戦略を進めるのです

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