関連する実験動画

Updated: Sep 9, 2025

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
07:41

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

Published on: February 20, 2018

9.0K

アロステル経路の計算設計は,リガンド選択的なGPCRシグナリングを再プログラムする

M Hijazi, D Keri, A Oggier

    bioRxiv : the preprint server for biology
    |September 2, 2025
    PubMed
    まとめ

    この研究では,Gタンパク質結合受容体 (GPCR) 配列の変異が信号伝達にどのように影響するかを予測する計算方法が導入されています. 研究者はGPCRを 再プログラムし 薬の発見とパーソナライズされた医療の 新たな道を開きました

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