関連する実験動画

Updated: Sep 9, 2025

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
10:26

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells

Published on: January 20, 2019

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B細胞における早期の補助剤反応性表遺伝子プログラムは,後のプラズマ細胞生存率と体内免疫の持続時間をインプリントする

Tyler J Ripperger1,2, Lucas J D'Souza1, James F Read1,3

  • 1Department of Immunobiology, University of Arizona College of Medicine, Tucson, AZ 85724, USA.

bioRxiv : the preprint server for biology
|September 2, 2025
PubMed
まとめ

耐久性のある抗体生成は プラズマ細胞だけでなく 初期のB細胞の表遺伝子プログラムに依存しています 初期のB細胞でZBTB20を削除すると,長期の抗体免疫が低下する.

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