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Updated: Sep 9, 2025

Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma
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Published on: August 31, 2022

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RAB5 NUCLEOTIDE BINDING 燃料へのβ酸化を促進する 肝細胞癌細胞の増殖

Kelly O Otakhor1, Mohd Ali Abbas Zaidi2, Rebecca Oberley-Deegan2

  • 1Department of Molecular Genetics and Cell Biology, University of Nebraska Medical Center, Omaha, NE.

bioRxiv : the preprint server for biology
|September 2, 2025
PubMed
まとめ

Rab5 GTPaseは,肝臓がん細胞における脂質滴動態を調節する. その活動は,脂質分解,ミトコンドリアのエネルギー生産,肝細胞癌 (HCC) 細胞増殖に不可欠であり,潜在的な治療目標を提供している.

キーワード:
肝細胞がん細胞内での取引脂質の滴リポファジーミトコンドリアの代謝ラブ5脂質代謝

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