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Updated: Sep 9, 2025

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MERS-CoVは,ウイルスの複製複合体での凝縮を阻害することによって,PKRの活性化を阻害する

Ebba K Blomqvist, Nicole Bracci, Helena Winstone

    bioRxiv : the preprint server for biology
    |September 2, 2025
    PubMed
    まとめ

    中東呼吸器症候群コロナウイルス (MERS-CoV) は,タンパク質キナーゼR (PKR) 経路に逆らいます. MERS-CoVのNS4aタンパク質は,先天的な免疫の重要なステップであるウイルス dsRNAのPKR凝縮を阻害することによって,PKR活性化を防ぐ.

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