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Updated: Sep 9, 2025

Streamlined Single Cell TCR Isolation and Generation of Retroviral Vectors for In Vitro and In Vivo Expression of Human TCRs
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Streamlined Single Cell TCR Isolation and Generation of Retroviral Vectors for In Vitro and In Vivo Expression of Human TCRs

Published on: September 10, 2017

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TCR ゲルムラインの多様性は,変数および結合アルファ鎖の遺伝子における自然選択の証拠を明らかにする

Sreekar Mantena, Ali Akbari, Soumya Raychaudhuri

    bioRxiv : the preprint server for biology
    |September 2, 2025
    PubMed
    まとめ

    T細胞受容体 (TCR) 遺伝子の遺伝的変異は適応免疫に大きく影響する. この研究はTCR遺伝子アレルをマッピングし,T細胞の選択と機能的影響を明らかにし,免疫多様性を説明しています.

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