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Updated: Sep 9, 2025

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イントロン保持はSTAT2機能を調節し,肺がんにおける免疫療法反応を予測する

Ryan P Englander1,2, Mattia Brugiolo1, Te-Chia Wu1

  • 1The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.

bioRxiv : the preprint server for biology
|September 2, 2025
PubMed
まとめ

代替RNAスプライシングは,肺がんにおける腫瘍免疫と免疫療法の反応に影響します. 特定のSTAT2イントロン保持は,チェックポイント阻害剤に対する患者の反応を予測し,潜在的なバイオマーカーを提供します.

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