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Updated: Sep 9, 2025

Extracting Modified Microtubules from Mammalian Cells to Study Microtubule-Protein Complexes by Cryo-Electron Microscopy
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Extracting Modified Microtubules from Mammalian Cells to Study Microtubule-Protein Complexes by Cryo-Electron Microscopy

Published on: March 3, 2023

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MATCAP1は特異的に膨張型チューブリンを結合し,オキシトシン化および ΔC2 α-チューブリンを生成する

Yang Yue, Takashi Hotta, Ryoma Ohi

    bioRxiv : the preprint server for biology
    |September 2, 2025
    PubMed
    まとめ

    メタロペプチダゼMATCAP1は,アルファチューブリンをオキソシン化 (ΔY) とΔC2で変異させる. 微小管の格子構造はMATCAP1の結合と活性を決定し,これらの翻訳後の改変 (PTM) を制御する.

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