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Updated: Sep 9, 2025

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SALL4は,YAP1に依存した悪性および再生性肝細胞を再プログラムするために必要です

Minwook Kim, Yoojeong Park, Rachel Covitz

    bioRxiv : the preprint server for biology
    |September 2, 2025
    PubMed
    まとめ

    スパルトのような転写因子4 (SALL4) は肝臓疾患における肝細胞の可塑性を調節する. SALL4は悪性腫瘍の変異に不可欠であり,再生再プログラムに影響を与え,潜在的な治療標的を提示する.

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