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Updated: Sep 9, 2025

A Method for Mouse Pancreatic Islet Isolation and Intracellular cAMP Determination
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自由脂肪酸受容体4のアゴニストは,マウスとヒトの島において異なるメカニズムでインスリン分泌を刺激する

Laura Reininger, Muhammad H Rehman, Amelia Bouabcha

    bioRxiv : the preprint server for biology
    |September 2, 2025
    PubMed
    まとめ

    自由脂肪酸受容体FFAR4の活性化により,インスリン分泌が増加します. マウスでは,ソマトスタチン阻害によって間接的に発生するが,ヒトの小島は,直接のベータ細胞効果を示し,FFAR4治療の種の違いを強調する.

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