関連する実験動画

Updated: Sep 9, 2025

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
07:41

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

Published on: February 20, 2018

9.0K

粘着GPCR信号伝導の分子特性

M Marfoglia, L Dumas, B S Yang

    bioRxiv : the preprint server for biology
    |September 2, 2025
    PubMed
    まとめ

    粘着Gタンパク質結合受容体 (aGPCR) は,GAINドメインを脱落させるか,または完結した結合を介して,異なる機械的な力経路を使用して信号を送る. この研究は,力方向がこれらのaGPCR活性化メカニズムをどのように制御するかを明らかにしています.

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