急性心不全と心臓タンポネードによって合併したチェックポイント阻害剤に関連した fulminant eosinophilic myo-pericarditis の症例報告
Yaqub Betz1, Selveras Zayed2, Francesco Moroni1
1Division of Cardiovascular Medicine, University of Virginia, PO Box 8000662, Charlottesville, VA 22908, USA.
European heart journal. Case reports
|September 2, 2025
まとめ
免疫チェックポイント阻害剤 (ICI) は致命的なエオシノフィル性心筋膜炎を引き起こす可能性があります. 早期の診断と生検は,特にタンポネードが疑われる場合に,この珍しいが重度のICI副作用の管理に不可欠です.
科学分野:
- 心臓病科
- 腫瘍学
- 免疫学
背景:
- 免疫チェックポイント阻害剤 (ICI) は,がん治療において重要な進歩をもたらします.
- しかし,ICIは,高い死亡率を伴う心筋炎を含む重度の有害事象と関連しています.
- ICIに関連した心筋炎は,生命を脅かす状態である fulminant eosinophilic myo- pericarditisとして現れます.
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