関連する実験動画

Updated: Sep 9, 2025

Genetic Manipulation of Cerebellar Granule Neurons In Vitro and In Vivo to Study Neuronal Morphology and Migration
09:07

Genetic Manipulation of Cerebellar Granule Neurons In Vitro and In Vivo to Study Neuronal Morphology and Migration

Published on: March 17, 2014

13.8K

CTNNB1/β-CATENINの進化的に保存された役割は,体カロスの発達を調節する

Arpan Parichha1,2,3, Debarpita Datta1, Amrita Singh1

  • 1Department of Biological Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India.

iScience
|September 2, 2025
PubMed
まとめ

CTNNB1の変異は,重要な脳構造である体 callosum (CC) の欠損を引き起こします. 特定のミドルラインの細胞におけるβ-カテニンの調節は,CCの発達に不可欠であり,CTNNB1症候群に関連する脳の異常を説明する可能性がある.

キーワード:
発達神経科学分子神経科学神経科学

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