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Updated: Sep 9, 2025

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NFKBとJAK-STAT経路を阻害することによって,シナージ的内皮炎を標的とする

Stijn A Groten1, Pieter Langerhorst1, Georgios Malamas1

  • 1Department of Molecular Hematology, Sanquin Research, Plesmanlaan 125, 1066 CX Amsterdam, the Netherlands.

iScience
|September 2, 2025
PubMed
まとめ

NFKBとJAK/STAT経路をターゲットにすることで,血管疾患における内皮炎症を減らすことができます. 阻害剤は,TNFαとIFNγの刺激によって誘発された主要な炎症反応と細胞外フォン・ウィレブランド因子ネットワークを阻害した.

キーワード:
生物化学細胞生物学プロテオミクス

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