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Updated: Sep 9, 2025

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
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Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter

Published on: March 27, 2020

7.0K

メニンは,HKDC1の転写を促進するためにYBX1核転移を調節し,臓がんの糖分解に影響を与える

Chenming Ni1, Jiacheng Yang1, Yebin Lu2

  • 1Department of Hepatobiliary Pancreatic Surgery, Changhai Hospital Affiliated to Navy Medical University, Shanghai, China.

iScience
|September 2, 2025
PubMed
まとめ

メニンタンパク質は,臓がんにおける糖分解と腫瘍の成長を抑制する. これはメニン- YBX1- HKDC1経路を通じて発生し,管腺癌の潜在的な治療標的となる.

キーワード:
癌について人間の代謝作用のメカニズム分子相互作用治療薬

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