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Updated: Sep 9, 2025

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research
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重度の急性腎臓損傷の詳細: 遡及研究から得られたPD-1/PD-L1抗体治療におけるリスク要因と結果

Yuemeng Wu1,2, Lingfan Luo2,3, Xin Sun4

  • 1Department of Nephrology, Dongyang Hospital (Affiliated Wenzhou Medical University), Jinhua, Zhejiang, China.

PeerJ
|September 2, 2025
PubMed
まとめ

免疫チェックポイント阻害剤 (ICI) は重度の急性腎損傷 (AKI) を引き起こす可能性があります. 高濃度のガンマグルタミルトランスファーゼ,利尿剤,NSAID,および細胞毒薬の使用は,PD- 1/ PD- L1療法を受けている患者における重度のAKIの主要な危険因子である.

キーワード:
免疫チェックポイント阻害剤腫瘍学リスク要因重度の急性腎臓損傷

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