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Updated: Sep 9, 2025

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IL-10/STAT5軸は,RAW264.7細胞におけるB7-H4発現を上調するためにmiR-140を抑制する

Dandan Zhu1, Guo Chen1,2, Pei Shen3

  • 1Department of Pathogen Biology, School of Medicine, Nantong University, Nantong, Jiangsu, China.

Frontiers in cellular and infection microbiology
|September 2, 2025
PubMed
まとめ

インターリューキン10 (IL-10) は,STAT5経由でmiR-140を抑制し,マクロファージのB7- H4発現を増加させます. これは,シストソミアシスにおける,IL-10によるB7-H4アップレギュレーションの新しいメカニズムを示しています.

キーワード:
B7-H4 についてIL-10 についてSTAT5 についてスキストソーマ・ジャポニカムmiR-140 について

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