関連する実験動画

Updated: Sep 9, 2025

Dissection of Enhancer Function Using Multiplex CRISPR-based Enhancer Interference in Cell Lines
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Dissection of Enhancer Function Using Multiplex CRISPR-based Enhancer Interference in Cell Lines

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免疫系調節における超強化剤:メカニズム,病理的再プログラム,および治療の機会

Xin Lai1, Caizhi Li2, Xinglinzi Tang2

  • 1The Seventh Clinical College of Guangzhou University of Chinese Medicine, Shenzhen, Guangdong, China.

Frontiers in immunology
|September 2, 2025
PubMed
まとめ

スーパーエンハンサー (SE) は,免疫細胞の発達と機能を制御する重要な表遺伝的ハブです. SEの調節不良は免疫疾患に寄与しますが,SEを標的とした新しい治療法は,免疫バランスを回復する見込みを示しています.

キーワード:
セル信号免疫システム病原性スーパーエンハンスター転写規制について

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