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関連する概念動画

Disorders of Leukocytes01:27

Disorders of Leukocytes

1.1K
Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune...
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Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

39
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
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関連する実験動画

Updated: Sep 9, 2025

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
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症例報告:ポリミキシンE関連可逆性白血病

Suxin Wan1, Jia-Quan Zhu2, Lihua Wang3

  • 1Department of Pharmacy, Chongqing University Three Gorges Hospital, Chongqing University, Chongqing, China.

Frontiers in immunology
|September 2, 2025
PubMed
まとめ
この要約は機械生成です。

抗生物質の最後の手段であるポリミキシンEは,白血病 (白血球数減少) を引き起こす可能性があります. このケーススタディは,患者の安全を確保するために,治療中に血液型をモニタリングすることの重要性を強調しています.

科学分野:

  • 感染症
  • 薬理学について
  • 血液学

背景:

  • ポリミキシンEは,多剤耐性細菌感染症に対する重要な抗生物質です.
  • ポリミキシンEの副作用には腎臓毒性および神経毒性が含まれます.
  • 白血病は潜在的ですが,あまり報告されていない副作用です.
キーワード:
クレブシエラ・プネモニア症例報告白血病ポリミキシンポリミキシンE

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