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Updated: Sep 9, 2025

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
08:07

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma

Published on: April 12, 2019

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進行中の骨肉腫の免疫マイクロ環境: 予後バイオマーカーおよび治療標的としてのPLEK

Yunpeng Zou1,2, Jianning Kang3, Shaopeng Zhu1

  • 1School of Clinical Medicine, Shandong Second Medical University, Weifang, Shandong, China.

Frontiers in immunology
|September 2, 2025
PubMed
まとめ

プラックストリン (PLEK) は,免疫を支える,代謝的に活発な腫瘍微環境を促進することによって,骨肉腫 (OS) の腫瘍抑制剤として作用します. 高いPLEKレベルは,より高い生存率と,OS細胞の悪性腫瘍の減少と相関する.

キーワード:
PLEK について免疫マイクロ環境分子バイオマーカーマルチオミクス分析オステオサルコマ単細胞RNAシーケンシング

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