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膠原腫に対する免疫反応における免疫チェックポイント:同じコインの2面

Oxana Musatova1, Vikas Kumar1,2, Konstantin Vinogradov1

  • 1Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russia.

Frontiers in immunology
|September 2, 2025
PubMed
まとめ

グリオマは免疫チェックポイントを利用して免疫抑制性腫瘍マイクロ環境 (TME) を生み出します. これらのチェックポイントを遮断することで 脳腫瘍に対する 新しい治療法が 期待できるかもしれません

キーワード:
T細胞の枯渇グリオブラストーマグリオマ免疫チェックポイント阻害剤免疫チェックポイント免疫反応ミエロイド抑制細胞規制T細胞

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