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Updated: Sep 9, 2025

Fibroblast-Derived 3D Matrix System Applicable to Endothelial Tube Formation Assay
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Fibroblast-Derived 3D Matrix System Applicable to Endothelial Tube Formation Assay

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コレクチン-11は,線維細胞の増殖を促進し,その活性化状態と細胞外マトリックス合成を調節する

Wan-Bing Chen1,2, Bo Cao2, Gang Li3

  • 1Department of Critical Care Medicine, The Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.

Frontiers in immunology
|September 2, 2025
PubMed
まとめ

コレクチン11 (CL-11) は,細胞外マトリックス生成を向上させ,重要なシグナル伝達経路を活性化することによって,腎臓の線維芽細胞の増殖と活性化を刺激する. CL- 11はEGFRとTGF- βRII受容体と相互作用し,その作用機構を明らかにする.

キーワード:
EGFRとTGF-βRII細胞増殖コレクチン-11フィブロブラスト機能腎臓の線維細胞

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