東中国におけるCOVID-19パンデミック期間中およびその後における小児性咳の流行の傾向と特徴

Linli Wang¹, Meiying Gao², Ying Chen¹

¹Department of Preventive Medicine, Children's Hospital, Zhejiang University School of Medicine, National Children's Regional Medical Center, National Clinical Research Center for Child Health, Hangzhou, Zhejiang, People's Republic of China.

Infection and drug resistance

|September 2, 2025

まとめ

COVID-19以降,中国東部の子供たちのうち,百日咳が急増しています. この病気はより高いリスクとより広い年齢の感受性を示し,更新されたワクチン接種戦略を必要とします.

科学分野:

小児科
感染症
流行病学について

背景:

Bordetella pertussisによって引き起こされる非常に伝染性の高い呼吸器疾患である百日咳は,依然として重要な小児の健康問題です.
特にCOVID-19 パンデミックと一致し,その後の世界的な咳の復活が観察されました.
東シナでは子供たちの間で百日咳の流行病学に顕著な変化が見られます

研究の目的:

小児患者の pertussis の流行病学的傾向を調査する.
東中国におけるCOVID-19のパンデミック期間およびその後の pertussisの特徴を分析する.
年齢による感受性の変化とリスク要因を特定する.

主な方法:

2022年1月から2024年11月までの間,疑われる pertussis の小児患者92,300人を遡って分析した.
臨床情報と pertussis テストの結果のために使用された検査データ.
統計分析のためにtテスト,Chi-squareテスト,および制限された立方スライン回帰を使用した.

主要な成果:

百日咳の陽性検出率は24.5%で,2024年4月に急増した.
6歳以上の子供と室外患者が最も高い検出率を示した (それぞれ36. 2%と37. 6%).
パンデミック後の分析は,パンデミック期間と比較して,より高いリスクとより幅広い年齢の感受性を明らかにした.

結論:

東中国では,COVID-19以降に顕著な流行病学的変化が観察され,小児性咳が再発しました.
年齢による感受性の増加とリスクの増加は,公衆衛生の介入の強化の必要性を強調しています.
ワクチン接種戦略を緊急に強化することは増えている pertussis の発生率と戦うために不可欠です.

キーワード:

COVID-19 流行について子供たち流行病学について百日咳百日咳百日咳復活する

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