関連する実験動画

Updated: Sep 9, 2025

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
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Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter

Published on: March 27, 2020

7.0K

SMURF1/2は,WNK1の安定性の新しい調節剤である

Ankita B Jaykumar1, Sakina Plumber1, Derk Binns1

  • 1Department of Pharmacology, UT Southwestern Medical Center, Dallas, TX 75390, USA.

Kinases and phosphatases
|September 2, 2025
PubMed
まとめ

成長因子β (TGF-β) 信号の変換は血管修復に不可欠です. この研究では,タンパク質キナーゼWNK1 (With No lysine 1) がTGF-βシグナル伝達と血管新生を制御するためにE3ユビキチンリガゼと相互作用する方法を明らかにしました.

キーワード:
ALK5 についてOSR1 についてSMURF1/2 についてスパックWNK1 について

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