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マンジバルの拡散性硬化性骨髄炎に対するゾレドロン酸の治療:抗吸収療法に関する症例報告と文献レビュー

Teruyuki Niimi1, Ryosuke Miwa1, Ken Kitagawa1

  • 1Division of Research and Treatment for Oral and Maxillofacial Congenital Anomalies, School of Dentistry, Aichi Gakuin University, Nagoya, JPN.

Cureus
|September 2, 2025
PubMed
まとめ

拡散性硬化性骨髄炎 (DSO) は珍しい下の疾患である. 抗吸収剤 (ARAs) は高い寛解率を示し,デノスマブよりもデノスマブよりも優れている.

キーワード:
抗吸収療法拡散性硬化性骨髄炎マンディブル持続する下の痛みゾレドロン酸

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Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...