傷 の 癒し に 対する 石榴 の 影響
Ilkay Halicioglu1, Nilgün Isiksacan2, Firat Baytekin3
1Gastrointestinal Surgery, University of Health Sciences, Gazi Yasargil Training and Research Hospital, Diyarbakir, TUR.
Cureus
|September 2, 2025
まとめ
石榴の抽出物は 傷の治癒を良くし 肝臓の損傷を減らすことができます セプシス前治療は最も有望な結果を示し,セプシス患者に潜在的な治療効果を示唆しました.
科学分野:
- 生物医学研究
- 薬理学について
- 傷の治癒に関する研究
背景:
- セプシスは傷の治癒を阻害し,全身の炎症によって臓器損傷を引き起こします.
- 石榴 (Punica granatum) 抽出物は抗酸化物質が豊富で,抗炎症性および組織治癒性があります.
研究 の 目的:
- セプシスモデルで傷の治癒に対する 石榴のエキスの効果を調査する.
- 石榴の抽出物の投与タイミング (セプシスの前と後の誘導) を評価する.
主な方法:
- Wistarのラットにおけるセプシス誘発のセカル・リガーションとパンクチャー (CLP) (n=38)
- グループには偽薬,セプシス,セプシスの前のナマケモノ,そしてセプシスの後のナマケモノ治療が含まれていました.
- 生化学的 (ALT,AST,尿素,クレアチニン) と組織病理学的パラメータは,手術後7日目に評価された.
主要な成果:
- アラニントランスアミナーゼ (ALT) 濃度が著しく低下した.
- セプシス後のナマケモノ治療は,クレアチニンのレベルを著しく低下させた.
- セプシスの前には,小粒球組織のスコアが低く,治癒が改善されたことが示されました.
結論:
- セプシスの前,ナマケモノのエキスを投与すると,セプシスによる肝損傷から保護できます.
- 石榴の抽出物は,症の傷の治癒を支援する補助療法として潜在的であることを示しています.
- この天然の製品は 病の治療に有益です
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