関連する実験動画

Updated: Sep 9, 2025

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
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Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels

Published on: July 4, 2016

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バイオセンサとX線結晶学を用いたアセチルコリン結合タンパク質のリガンド誘発型変化の検出と特徴付け

Edward A FitzGerald1,2, Daniela Cederfelt1, Daria Kovryzhenko1

  • 1Department of Chemistry - BMC, Uppsala University Sweden helena.danielson@kemi.uu.se.

RSC chemical biology
|September 2, 2025
PubMed
まとめ

リンガンド結合によるタンパク質構造の変化を分析することは困難である. この研究は,様々なバイオセンサがこれらの変化を検出し,タンパク質-リガンドの相互作用を包括的に理解するためにX線結晶学を補完することを示しています.

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