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Updated: Sep 9, 2025

Microfluidics in Assessing Platelet Function
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パルボシクリブとリバロキサバンまたはアピキサバンのインビヴォの薬物相互作用: 薬剤の露出量増加と投与量調整への影響

Wenyu Du1,2, Zihan Liu1,2, Ying Li2

  • 1Graduate School, Hebei Medical University, Shijiazhuang, 050017, People's Republic of China.

Drug design, development and therapy
|September 2, 2025
PubMed
まとめ

パルボシクリブは,アピキサバンとリバロキサバンの吸収とクリアランスに影響を与えることで,アピキサバンとリバロキサバンの暴露を大幅に増加させます. ネズミで観察されたこの相互作用は,併用薬の投与量を調整する必要があることを示唆している.

キーワード:
アピキサバン癌に関連した静脈血栓塞栓症薬物相互作用パルボシクリブリバロキサバン

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