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Updated: Sep 9, 2025

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コカインへの嗜好が育つには,前膜皮質内のAMPA/カイナート受容体の活性化が必要である

Laura L Huerta Sanchez1, Mirette G Tadros1, Hoa H T Doan1

  • 1Department of Psychological and Brain Sciences, University of California, Santa Barbara, Santa Barbara, CA, United States.

Frontiers in psychiatry
|September 2, 2025
PubMed
まとめ

中間前頭皮質にあるアルファ-アミノ-3-ヒドロキシ-5-メチル-4-イソクサゾールプロピオン酸 (AMPA) 受容体は,コカインへの渇望の育成に不可欠です. これらの受容体をプリリンビック領域で遮断することで 離脱後期における渇望が減った.

キーワード:
AMPA受容体薬物への渇望麻薬の嗜好を育成するサクラロースの渇望の育成前頭皮質

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