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Updated: Sep 9, 2025

Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure
09:38

Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure

Published on: August 11, 2017

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CircPLK1は,ETS1を調節し,トリプルネガティブの乳がんにアントラサイクリン耐性を与える

Danian Dai1, Jinhui Zhang2, Yunxian Mo2

  • 1Department of Plastic and Peripheral Vascular Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong Province, China.

Journal of translational internal medicine
|September 2, 2025
PubMed
まとめ

循環型RNA circPLK1は,三重陰性乳がん (TNBC) のアントラサイクリン化学療法に対する耐性を促進する. circPLK1を阻害することは,予後が悪いTNBC患者にとって新しい治療戦略を提供することができる.

キーワード:
ETS1 についてPLK1 についてアントラサイクリン耐性円形のRNAトリプルネガティブ乳がん

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