不眠症の癌生存者における不安に対する治療対認知行動療法:ランダム化臨床試験の探索分析

Eunbin Kwag¹, Xiaotong Li¹, Sheila Garland²

¹Integrative Medicine Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States.

Integrative medicine research

|September 2, 2025

まとめ

治療と不眠症の認知行動療法 (CBT-I) は,がんの生存者における不安と不眠症を効果的に軽減します. CBT-Iは相互に関連した症状改善を示したが,治療は症状を独立して対処した.

科学分野:

腫瘍学
精神科
統合医療

背景:

不安と不眠症はがんを生き延びた患者でよく同時発症します
この集団における不安と不眠の両方を同時に標的とする確立された介入はありません.

研究の目的:

併発性不安症と不眠症の治療における治療とCBT-Iの有効性を比較する
治療反応と症状の軽減の関係を調べる

主な方法:

ダブルセンターでのランダム化比較効果試験では 76人の癌の生存者が関わり,不安が高まった.
参加者は治療またはCBT-Iを8週間,フォローアップは20週間受けました.
病院の不安・うつ病・不安スケール (HADS- A) を用いて,初期,第8週,第20週で不安を評価した.

主要な成果:

治療とCBT-Iの両方では,HADS-Aスコアをベースラインから週8と週20で有意に低下させました (p < 0. 001).
2つのグループでは,不安の軽減に有意な違いは認められなかった (p=0. 85).
CBT- Iでは,不眠症に反応した患者では,不眠症に反応しなかった患者よりも不安が軽減された (p=0. 0046 8週,p=0. 038 20週).

結論:

治療とCBT-Iは併発性不安症と不眠症の治療に有効です
CBT-Iは不安と不眠症を相互に関連した方法で改善します
治療はこれらの症状をより独立に対処することで利点をもたらします

キーワード:

治療不安について CBT-I 癌を生き延びた人不眠症

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