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Updated: Sep 9, 2025

Transarterial Administration of Oncolytic Viruses for Locoregional Therapy of Orthotopic HCC in Rats
08:55

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腫瘍性rVSV-NDVによる同胞死は,ヒトの肺がん細胞における免疫性アポトーシスとネクロプトーシスを動的に活性化させる

Fabian Kortum1, Nina Hartmann1, Alexander Bryan1

  • 1TUM School of Medicine - Clinical Department of Internal Medicine II, TUM University Hospital, 81675 Munich, Germany.

Molecular therapy. Oncology
|September 2, 2025
PubMed
まとめ

rVSV- NDVのような融合性ウイルスを用いた腫瘍解毒性ウイルス治療は,アポトーシスとネクロプトーシス経路を誘発することで免疫性細胞死を引き起こす. 免疫反応が強化され 癌の治療法として 有望な結果が得られます

キーワード:
DCアクティベーションMT:定期発行アポトーシスガンに対する免疫療法細胞融合免疫細胞死ネクロプトーシス腫瘍性ウイルスrVSVrVSV-NDV についてシンシティアル死

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