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Updated: Sep 9, 2025

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
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Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

Published on: July 25, 2020

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HR+/ HER2- 進行/ 転移性乳がんの高齢者およびBIPOC患者におけるCDK4/ 6iの実用的な有効性と安全性: 更新された体系的な文献レビュー

Nadia Harbeck1, Adam Brufsky2, Chloe Grace Rose3

  • 1Breast Center, Department of Gynecology & Obstetrics & Comprehensive Cancer Center Munich, Ludwig-Maximilians-University (LMU) University Hospital, Munich, Germany.

Frontiers in oncology
|September 2, 2025
PubMed
まとめ

シクリン依存キナーゼ4/6阻害剤 (CDK4/ 6i) は,進行したHR+/ HER2乳がんの高齢患者およびBIPOC患者において有効性と良好な耐受性を示しています. 現実の世界での証拠は,特に 代表が少ない集団の利用を支持しています.

キーワード:
BIPOC (バイポック)CDK4/6i乳房高齢者メタスタシス現実世界の証拠体系的な文献レビュー

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