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Updated: Sep 9, 2025

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
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An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis

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小児肝細胞がんにおける免疫チェックポイント阻害剤の安全性と臨床効果:症例報告と文献のレビュー

Xiaoting Zhong1,2,3,4,5, Xuejiao Wen1,2,3,4,5, Xinping Wang2

  • 1Department of Oncology, The First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi, China.

Frontiers in oncology
|September 2, 2025
PubMed
まとめ

免疫チェックポイント阻害剤 (ICI) の小児肝細胞癌 (HCC) 治療は調査中です. いくつかの患者は安定した疾患を示したが,HCCの子供におけるICIの安全性と有効性を確立するためにさらなる研究が必要である.

キーワード:
HCC について有害事象免疫チェックポイント阻害剤免疫療法小児肝細胞がん

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関連する概念動画

Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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