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Updated: Sep 9, 2025

Author Spotlight: Developing a Rat Model for Pouchitis Research and Treatment
04:05

Author Spotlight: Developing a Rat Model for Pouchitis Research and Treatment

Published on: May 31, 2024

475

Artrestan (サクビトリル/バルサタン) の再利用により,ラットの潰瘍性大腸炎における抗炎症およびフィブリノリチス作用が明らかになった

Khatereh Kharazmi1,2, Seyedeh Elnaz Nazari1, Moein Eskandari3

  • 1Department of Medical Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Iranian journal of basic medical sciences
|September 2, 2025
PubMed
まとめ

アルトレスタンは,特にメサラジンと併用して,疾患の活動と炎症を軽減することで,潰瘍性大腸炎 (UC) の治療に有望であることが示されています. この組み合わせ治療はUC動物モデルで抗酸化物質のレベルを効果的に改善し,線維症を減少させた.

キーワード:
アートレスタン (サクビトリル/バルサタン)繊維症炎症メサラジン潰瘍性大腸炎

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