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Updated: Sep 9, 2025

Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages
06:52

Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages

Published on: May 21, 2018

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自然に発生する炎症体調節剤としてのレスベラトロール:健康と病気への影響

Mahboobeh Ghasemzadeh Rahbardar1, Amirhossein Sahebkar2,3,4

  • 1Clinical Research Development Unit, Shahid Hasheminejad Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.

Iranian journal of basic medical sciences
|September 2, 2025
PubMed
まとめ

レスベラトロールは天然の化合物で 炎症を制御する鍵となる炎症体である 炎症ソームを調節します このレビューでは,NLRP3炎症体のような経路を阻害することによって,炎症を軽減し,病気を治療する可能性を調査しています.

キーワード:
心血管疾患サイトカイン消化器系疾患炎症インタールイキン神経系疾患酸化ストレスフィトケミカル

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Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells

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Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response12:50

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response

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Inflammatory Response01:28

Inflammatory Response

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The Unfolded Protein Response01:37

The Unfolded Protein Response

The ER is the hub of protein synthesis in a cell. It has robust systems to quality control protein folding and also for degradation of terminally misfolded proteins. Under normal conditions, a small proportion of misfolded proteins that cannot be salvaged need to be transported to the cytoplasm by the ER-associated degradation or ERAD pathways. However, if the ERAD cannot handle the misfolded proteins, the cell activates the unfolded protein response or UPR to adjust the protein folding...
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NF-κB-dependent Signaling Pathway

The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
NF-κB-dependent Signaling Mechanism
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