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Updated: Sep 9, 2025

Molecular Modulation by Lentivirus-Delivered Specific shRNAs in Endoplasmic Reticulum Stressed Neurons
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Molecular Modulation by Lentivirus-Delivered Specific shRNAs in Endoplasmic Reticulum Stressed Neurons

Published on: April 24, 2021

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炎症誘発性ストレスは,セラミド濃縮β細胞EV亜集団の中性スフィンゴミエリンゼ2基生成を活性化させる

Jerry Xu1,2, Irene Amalaraj1,2, Andre De Oliveira1,2

  • 1Department of Pediatrics, Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN.

Diabetes
|September 2, 2025
PubMed
まとめ

炎症は臓ベータ細胞のストレスを引き起こし,小さな細胞外膀 (EVs) のセラミドを増加させます. これらのEVはインスリンシグナル伝達に影響を及ぼし 1型糖尿病に潜在的に貢献します

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