関連する実験動画

Updated: Sep 9, 2025

Looking for Driver Pathways of Acquired Resistance to Targeted Therapy: Drug Resistant Subclone Generation and Sensitivity Restoring by Gene Knock-down
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Looking for Driver Pathways of Acquired Resistance to Targeted Therapy: Drug Resistant Subclone Generation and Sensitivity Restoring by Gene Knock-down

Published on: December 11, 2017

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HER2陽性転移性乳がんに対するパルボシクリブとトラストズマブ: SOLTI-1303- PATRICIA試験のコホートAとBの最終的な全生存結果

T Pascual1, G Villacampa2, M Oliveira3

  • 1SOLTI Cancer Research Group, Barcelona, Spain; Department of Medical Oncology, Cancer Institute and Blood Disorders, Hospital Clínic de Barcelona, Barcelona, Spain; Translational Genomics and Targeted Therapies in Solid Tumors, August Pi I Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain; Medicine Department, University of Barcelona, Barcelona, Spain.

ESMO open
|September 2, 2025
PubMed
まとめ

PATRICIA試験では,ホルモン受容体陽性/ HER2陽性転移性乳がんにおいて,パルボシクリブとトラストズマブが有望な全生存率を示した. 遺伝子発現プロファイリングにより,より良い患者選択と治療戦略のためのバイオマーカーが特定されました.

キーワード:
HR陽性/HER2陽性バイオマーカー遺伝子発現プロファイリング転移した乳がんパルボシクリブトラストズマブ

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