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Updated: Sep 9, 2025

Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats
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ヒトのスクレロスティンにインスパイアされた短いペプチドは,骨粗鬆症を逆転させ,Wnt経路を介して関節変退を抑制する

Shivani Sharma1, Chirag Kulkarni2, Neeraj K Verma3

  • 1Division of Endocrinology and Centre for Research in ASTHI, CSIR-Central Drug Research Institute, Council of Scientific and Industrial Research, Lucknow 226031, India; Division of Nephrology and Hypertension, Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|September 2, 2025
PubMed
まとめ

2つの新しいスクレロスティン由来ペプチド,SC-1とSC-3は,治療上の希望を示しています. SC-1は骨の形成を促し,SC-3は異常な骨の成長を抑制し,軟骨の修復を促進することで,骨格炎を標的とする.

キーワード:
ハイドロゲルの配達骨関節炎骨粗鬆症ペプチド療法スクレロスティン信号は出ない

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