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Updated: Sep 9, 2025

Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss
07:03

Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss

Published on: July 19, 2024

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代謝機能障害に関連するステアトヘパチスの治療のための肝臓を標的とするリン酸甲状腺ホルモン受容体アゴニストの設計,合成,および生物学的評価

Chao Lin1, Peiwu Li2, Yixing Zhang2

  • 1Shandong College of Traditional Chinese Medicine, Department Traditional Chinese Medicine, Yantai, Shandong 264100, China.

Bioorganic chemistry
|September 2, 2025
PubMed
まとめ

研究者は,代謝機能障害に関連した脂肪肝炎 (MASH) の治療のために,肝臓を標的とする新しい化合物29aを開発しました. この有望な新薬候補は,強力な抗MASH効果と,臨床前試験で良好な安全性プロファイルを示しています.

キーワード:
代謝機能障害に関連したステア肝炎甲状腺ホルモン受容体 βVK2809 について

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