関連する実験動画

Updated: Sep 9, 2025

Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway
07:15

Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway

Published on: August 23, 2024

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MDL-800は炎症および代謝機能障害に対する保護:ネズミのNFκB,AMPK,PPAR信号のクロス調節におけるSIRT6の役割

Rabab S Hamad1, Waseem Ali Hasan2, Sameh Saber3

  • 1Biological Sciences Department, College of Science, King Faisal University, Al Ahsa 31982, Saudi Arabia.

International immunopharmacology
|September 2, 2025
PubMed
まとめ

MDL-800によるSirtuin 6 (SIRT6) の薬理学的活性化は,ラットにおける代謝症候群 (MetSyn) を効果的に治療する. このアプローチは生存率,代謝機能を改善し,炎症を軽減し,SIRT6をメットシンの重要な治療目標として強調します.

キーワード:
炎症インスリン抵抗性MDL-800 についてNFκB/AMPK/PPARシグナリングOSS-128167 についてSIRT6/メタボリックシンドローム

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